Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.54 |
| ▸ | IL1RN | P18510 | 3/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16344017 | 1.00 | MEN1 (0.58) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL12819866 | 0.99 | MEN1 (0.57) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| SCHEMBL12819471 | 0.99 | MEN1 (0.57) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL16343490 | 0.98 | MEN1 (0.56) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL12819559 | 0.98 | MEN1 (0.56) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| SCHEMBL16381767 | 0.95 | MEN1 (0.60) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL16343724 | 0.94 | MEN1 (0.59) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| Hydrochloric Acid SCHEMBL12819679 | 0.94 | MEN1 (0.59) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| SCHEMBL16377245 | 0.94 | MEN1 (0.59) | MEN1KMT2AHCRTR1ERAP2ERAP1 | |
| SCHEMBL16381769 | 0.94 | MEN1 (0.59) | MEN1KMT2AHCRTR1ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103502215-A | Prodrugs of D-gamma-glutamyl-D-tryptophan and D-gamma-glutamyl-L-tryptophan | APOTEX TECHNOLOGIES INC | 2014-01-08 | — | — | CN | disclosed |