Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.54 |
| ▸ | PPARA | Q07869 | 11/20 | 0.54 |
| ▸ | PPARD | Q03181 | 9/20 | 0.54 |
| ▸ | USP5 | P45974 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096624 | 0.92 | PPARG (0.51) | PPARGPPARAPPARDUSP5GALK1 | |
| SCHEMBL12096906 | 0.83 | PPARG (0.50) | PPARGPPARAPPARDUSP5CNR1 | |
| SCHEMBL12096720 | 0.78 | PPARG (0.54) | PPARGPPARAPPARDGALK1RORC | |
| SCHEMBL12096795 | 0.78 | PPARG (0.54) | PPARGPPARAPPARDGALK1RORC | |
| SCHEMBL12096901 | 0.78 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL12096713 | 0.77 | PPARG (0.53) | PPARGPPARAPPARDRORC | |
| SCHEMBL12096612 | 0.76 | PPARG (0.70) | PPARGPPARAPPARDRORC | |
| SCHEMBL12096644 | 0.76 | PPARG (0.70) | PPARGPPARAPPARDPTGER2RORC | |
| SCHEMBL12096722 | 0.76 | PPARG (0.52) | PPARGPPARAPPARDGALK1RORC | |
| SCHEMBL12096657 | 0.75 | PPARG (0.53) | PPARGPPARAPPARDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554006-A | Use of indole derivatives as nurr-1 activators for the application thereof as a medicament for the treatment of parkinson's disease | FOURNIER LAB SA | 2014-02-05 | — | — | CN | disclosed |