SCHEMBL27951815

SCHEMBL27951815

NS(=O)(=O)C1C=Cc2cccc3cccc1c23

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
CES2 O00748 1/20 0.31
ALDH1A1 P00352 1/20 0.31
BCHE P06276 1/20 0.31
CES1 P23141 1/20 0.31
MCL1 Q07820 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27579326 0.90 MEN1 (0.33) MEN1MAPTMAPK1KMT2ACES2
SCHEMBL4564629 0.83 MEN1 (0.31) MEN1MAPTMAPK1KMT2ACES2
Hydrochloric Acid SCHEMBL27785413 0.82 MEN1 (0.30) MEN1MAPTMAPK1KMT2A
SCHEMBL5709695 0.82 MEN1 (0.30) MEN1MAPTMAPK1KMT2A
SCHEMBL28768752 0.81
SCHEMBL27721446 0.81
SCHEMBL30232400 0.80 HTR2A (0.39) MEN1MAPTKMT2AALDH1A1CA1
SCHEMBL2902860 0.80 HTR2A (0.39) MEN1MAPTKMT2AALDH1A1CA1
SCHEMBL10437221 0.80
SCHEMBL10447784 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103570653-A Heterocyclic compound, organic light-emitting device including the same , and organic light-emitting display device SAMSUNG DISPLAY CO LTD 2014-02-12 CN disclosed