SCHEMBL27953232

SCHEMBL27953232

O=C(C1(CO)CC1)C1(CO)CC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11517742 0.85 CYP2C19 (0.46) CYP4F2CYP4A11
SCHEMBL252560 0.78 CYP2C19 (0.44)
SCHEMBL1815192 0.78
SCHEMBL13290227 0.75
SCHEMBL10246827 0.75
SCHEMBL9631277 0.72 GAA (0.36)
SCHEMBL2924831 0.71 TSHR (0.30)
SCHEMBL23893219 0.69
SCHEMBL12230984 0.69
SCHEMBL15731435 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619817-A Novel bicyclic nitrogen containing heteroaryl TGR5 receptor modulators BRISTOL MYERS SQUIBB CO 2014-03-05 CN disclosed