Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.68 |
| ▸ | PIM3 | Q86V86 | 9/20 | 0.65 |
| ▸ | PIM2 | Q9P1W9 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689315 | 0.81 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14689058 | 0.79 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14688650 | 0.78 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14690142 | 0.77 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14689243 | 0.77 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14689216 | 0.76 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14713855 | 0.76 | PIM1 (0.74) | PIM1PIM3PIM2 | |
| SCHEMBL14713876 | 0.75 | PIM1 (0.77) | PIM1PIM3PIM2 | |
| SCHEMBL14690138 | 0.75 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL14688507 | 0.74 | PIM1 (1.00) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103874700-A | Pyrazolo [3,4-c ] pyridine compounds and methods of use | HOFFMANN LA ROCHE | 2014-06-18 | — | — | CN | disclosed |