Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586009 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL1691931 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL8925891 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL4640897 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL668131 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL3159815 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL80184 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL7920927 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL194425 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 | |
| SCHEMBL1562330 | 0.89 | BID (0.59) | KAT8BIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103790043-A | Environment-friendly high-temperature leveling agent and preparation method thereof | HANGZHOU MEIGAO HUAYI CHEM CO LTD | 2014-05-14 | — | — | CN | claimed |
| CN-103790043-A | Environment-friendly high-temperature leveling agent and preparation method thereof | HANGZHOU MEIGAO HUAYI CHEM CO LTD | 2014-05-14 | — | — | CN | disclosed |