Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27811990 | 1.00 | TDP1 (0.41) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL27811987 | 1.00 | TDP1 (0.41) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL27958747 | 0.88 | TDP1 (0.38) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL28317306 | 0.86 | TDP1 (0.42) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL27972683 | 0.86 | TDP1 (0.42) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL27991337 | 0.86 | TDP1 (0.42) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL28095477 | 0.85 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28008571 | 0.83 | TDP1 (0.39) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL28008570 | 0.83 | TDP1 (0.39) | TDP1LTA4H | |
| Tert-Butyl Formate SCHEMBL27647078 | 0.79 | TDP1 (0.54) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703781-A | Preparation method of ibrutinib | 山东新时代药业有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-113929686-A | Preparation method of ibrutinib | 鲁南制药集团股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-113929685-A | Preparation method of ibrutinib intermediate | 鲁南制药集团股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-107501274-B | It can be used as the compound of ATR kinase inhibitor | Votex Pharmaceutical Co., Ltd. (US) | 2019-11-22 | — | — | CN | disclosed |
| CN-107501275-B | It can be used as the compound of ATR kinase inhibitor | Votex Pharmaceutical Co., Ltd. (US) | 2019-11-22 | — | — | CN | disclosed |
| CN-109790146-A | Medical compounds | 阿尔麦克探索有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104903325-A | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMA | 2015-09-09 | — | — | CN | disclosed |
| CN-104470925-A | Imidazotriazinecarbonitriles useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2015-03-25 | — | — | CN | disclosed |
| CN-103874493-A | Inhibitors of the renal outer medullary potassium channel | MERCK SHARP & DOHME | 2014-06-18 | — | — | CN | disclosed |