Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | IAPP | P10997 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404977 | 0.85 | MAPT (0.53) | MAPTLMNAIAPPPTGS1ALDH1A1 | |
| SCHEMBL1404976 | 0.85 | MAPT (0.53) | MAPTLMNAIAPPPTGS1ALDH1A1 | |
| SCHEMBL11210618 | 0.79 | ESR1 (0.60) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL11210622 | 0.79 | ESR1 (0.60) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL26601267 | 0.79 | MAPT (0.67) | MAPTLMNAIAPPPTGS1ALDH1A1 | |
| SCHEMBL1404884 | 0.77 | MAPT (0.59) | MAPTLMNAIAPPPTGS1ALDH1A1 | |
| SCHEMBL27959041 | 0.77 | MAPT (0.59) | MAPTLMNASMN1; SMN2IAPPPTGS1 | |
| SCHEMBL1404883 | 0.77 | MAPT (0.59) | MAPTLMNAIAPPPTGS1ALDH1A1 | |
| SCHEMBL17225904 | 0.77 | MAPT (0.59) | MAPTLMNASMN1; SMN2IAPPPTGS1 | |
| SCHEMBL332380 | 0.77 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103755715-A | Benzofuran [2, 3-c] pyridine compound and synthetic method thereof | UNIV WUHAN TECH | 2014-04-30 | — | — | CN | claimed |
| CN-103755715-B | Cumarone is [2,3-c] pyridine compounds and synthetic method thereof also | WUHAN UNIVERSITY OF TECHNOLOGY (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-103755715-A | Benzofuran [2, 3-c] pyridine compound and synthetic method thereof | UNIV WUHAN TECH | 2014-04-30 | — | — | CN | disclosed |