Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179855 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL29759243 | 0.81 | — | — | |
| SCHEMBL22734360 | 0.81 | — | — | |
| Bromide SCHEMBL28140703 | 0.81 | — | — | |
| Acetic Acid SCHEMBL11235050 | 0.74 | — | — | |
| Trimethylammonium SCHEMBL27791965 | 0.74 | — | — | |
| Trimethylammonium SCHEMBL27698301 | 0.71 | HIF1A (0.60) | ALDH1A1HIF1ATSHRTDP1MAPK1 | |
| Glutaral SCHEMBL27561663 | 0.71 | HIF1A (0.71) | ALDH1A1HIF1ATSHRTDP1MAPK1 | |
| Oxirane SCHEMBL5079565 | 0.71 | — | — | |
| SCHEMBL18477621 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596988-B | Alkyl-modified vinyl acetal based polymer and composition | KURARAY CO.,LTD. (JP) | 2016-04-06 | — | — | CN | disclosed |
| CN-103476807-B | Polyoxyalkylene-modified vinyl acetal based polymer and containing its composition | KURARAY CO.,LTD. (JP) | 2016-01-13 | — | — | CN | disclosed |
| CN-105175590-A | Polyvinyl acetal resin | KURARAY CO | 2015-12-23 | — | — | CN | disclosed |
| CN-103068859-B | Polyvinyl acetal resin, slurry composition thereof, ceramic green sheet, and multilayer ceramic capacitor | KURARAY CO.,LTD. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-103842313-A | Slurry composition, ceramic green sheet, and laminated ceramic capacitor | KURARAY CO | 2014-06-04 | — | — | CN | disclosed |