Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540067 | 0.89 | PTPN1 (0.48) | HTR6PTPN1HTR1AHTR1DHTR2C | |
| SCHEMBL27962075 | 0.82 | KDM1A (0.37) | HTR6GSK3BHTR1AHTR1DHTR2C | |
| SCHEMBL5541961 | 0.81 | CYP11B1 (0.44) | HTR6PTPN1HTR1AMAOAMAOB | |
| SCHEMBL5544391 | 0.80 | PTPN1 (0.44) | HTR6PTPN1HTR1AHTR1DHTR2C | |
| SCHEMBL27962074 | 0.79 | SMN1; SMN2 (0.34) | HTR6 | |
| SCHEMBL5542384 | 0.79 | PTPN1 (0.48) | PTPN1HTR1AHTR1DHTR2CMTNR1A | |
| SCHEMBL27822551 | 0.75 | MAOB (0.46) | PTPN1MAOAMAOB | |
| SCHEMBL27962009 | 0.73 | KDM1A (0.35) | — | |
| SCHEMBL5543456 | 0.72 | CYP11B1 (0.41) | HTR6PTPN1HTR1AMAOAMAOB | |
| SCHEMBL5541957 | 0.70 | PTPN1 (0.41) | HTR6PTPN1HTR1AHTR1DHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906512-A | Tetracyclic heterocyclic compounds and methods of use thereof for treating viral diseases | MERCK SHARP & DOHME | 2014-07-02 | — | — | CN | disclosed |