Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962161 | 0.86 | GSK3B (0.37) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14740995 | 0.83 | NPC1 (0.38) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14740974 | 0.82 | GSK3B (0.37) | GSK3BTOP1NPC1MAPTKDM4E | |
| SCHEMBL14741217 | 0.81 | GSK3B (0.37) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14741090 | 0.80 | TOP1 (0.38) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14741193 | 0.80 | TOP1 (0.36) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14740841 | 0.80 | MAPT (0.36) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14741015 | 0.79 | PTGS1 (0.36) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14741057 | 0.78 | PPARG (0.39) | GSK3BTOP1NPC1MEN1KMT2A | |
| SCHEMBL14745288 | 0.78 | MAPT (0.36) | GSK3BTOP1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889223-A | Antibacterial compounds and methods for use | PTC THERAPEUTICS INC | 2014-06-25 | — | — | CN | claimed |
| CN-103889223-A | Antibacterial compounds and methods for use | PTC THERAPEUTICS INC | 2014-06-25 | — | — | CN | disclosed |