Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.55 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15447037 | 0.84 | PPARG (0.52) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL17763412 | 0.83 | CYP1A2 (0.56) | — | |
| SCHEMBL14210014 | 0.80 | PPARG (0.65) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL7278634 | 0.78 | SLC7A5 (0.50) | FFAR1PPARGPPARALTA4HPPARD | |
| SCHEMBL9081822 | 0.77 | CYP1A2 (0.71) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL12379284 | 0.76 | SLC7A5 (0.70) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL1768559 | 0.76 | SLC7A5 (0.70) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL11432241 | 0.76 | FFAR1 (0.65) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL515521 | 0.76 | SLC7A5 (0.70) | FFAR1PPARGPPARALTA4HSRD5A2 | |
| SCHEMBL29584001 | 0.76 | SLC7A5 (0.70) | FFAR1PPARGPPARALTA4HSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083821-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-17 | — | — | CN | disclosed |
| CN-103936819-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-07-23 | — | — | CN | disclosed |