Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 3/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809895 | 0.90 | FFAR1 (0.58) | FFAR1GRM5GRM4KCNH2 | |
| SCHEMBL30214468 | 0.90 | FFAR1 (0.58) | FFAR1GRM5GRM4KCNH2 | |
| Hydrochloric Acid SCHEMBL19668206 | 0.88 | FFAR1 (0.57) | FFAR1GRM5GRM4KCNH2 | |
| SCHEMBL14993421 | 0.86 | FFAR1 (0.52) | FFAR1ERN1GRM5 | |
| SCHEMBL352291 | 0.79 | GRM5 (0.65) | GRM5KCNH2 | |
| SCHEMBL31673060 | 0.79 | GRM5 (0.55) | FFAR1ERN1GRM5KCNH2 | |
| SCHEMBL30047851 | 0.77 | FFAR1 (0.62) | FFAR1ERN1GRM5 | |
| SCHEMBL3648381 | 0.77 | FFAR1 (0.62) | FFAR1ERN1GRM5 | |
| SCHEMBL5569770 | 0.76 | GRM5 (0.53) | FFAR1ERN1GRM5KCNH2 | |
| SCHEMBL7873393 | 0.76 | FFAR1 (0.49) | FFAR1ERN1GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958476-A | N- (4-quinolinylmethyl) sulfonamide derivatives and their use as anthelmintics | DU PONT | 2014-07-30 | — | — | CN | disclosed |