SCHEMBL27965992

SCHEMBL27965992

N#Cc1cccc(-n2cncn2)c1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 7/20 0.51
CYP2A6 P11509 1/20 0.49
NOTUM Q6P988 1/20 0.48
ADORA3 P0DMS8 6/20 0.46
ADORA2A P29274 5/20 0.46
ADORA1 P30542 5/20 0.46
DRD2 P14416 1/20 0.45
DRD3 P35462 1/20 0.45
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12138940 0.82 KDM4E (0.42) CYP2A6ADORA3ADORA2AADORA1KDM4E
SCHEMBL11926858 0.82 CYP2A6 (0.62) CYP2A6KDM4EALDH1A1SMN1; SMN2
SCHEMBL20817508 0.79 CYP1A2 (0.52) KDM4EALDH1A1
SCHEMBL30618807 0.79 CYP1A2 (0.52) KDM4EALDH1A1
SCHEMBL2270763 0.79 KDM4E (0.55) CYP2A6NOTUMKDM4EALDH1A1SMN1; SMN2
SCHEMBL4702337 0.75 GRM5 (0.55) GRM5NOTUMDRD2DRD3KDM4E
SCHEMBL6271346 0.74 CYP2A6 (0.53) CYP2A6KDM4EALDH1A1SMN1; SMN2
SCHEMBL1788007 0.74 CYP2A6 (0.53) CYP2A6KDM4EALDH1A1SMN1; SMN2
SCHEMBL1187043 0.74 CYP2A6 (0.53) CYP2A6KDM4EALDH1A1SMN1; SMN2
SCHEMBL9454459 0.74 CYP2A6 (0.53) CYP2A6KDM4EALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106165684-B Pesticidal compositions and methods relating thereto 陶氏益农公司 2019-06-14 CN disclosed
CN-103732567-A Dihydrofuran derivatives as pesticidal compounds SYNGENTA PARTICIPATIONS AG 2014-04-16 CN disclosed