Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.62 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | BAD | Q92934 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 6/20 | 0.55 |
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68062 | 0.91 | PTPRC (0.72) | PTPRCTP53TSHRTTRKDM4E | |
| SCHEMBL69805 | 0.91 | PTPRC (0.72) | PTPRCTP53TSHRTTRKDM4E | |
| Hydrochloric Acid SCHEMBL7086253 | 0.88 | PTPRC (0.69) | PTPRCTP53TSHRTTRKDM4E | |
| Hydrochloric Acid SCHEMBL6925907 | 0.88 | PTPRC (0.69) | PTPRCTP53TSHRTTRKDM4E | |
| Hydrochloric Acid SCHEMBL5667643 | 0.88 | PTPRC (0.69) | PTPRCTP53TSHRTTRKDM4E | |
| Hydrochloric Acid SCHEMBL11425710 | 0.88 | PTPRC (0.69) | PTPRCTP53TSHRTTRKDM4E | |
| SCHEMBL27867340 | 0.86 | TP53 (0.55) | PTPRCBCL2L1BADRXRARXRB | |
| SCHEMBL4620446 | 0.85 | MAP4K4 (0.56) | PTPRCRXRARXRBTTREGFR | |
| SCHEMBL27883746 | 0.84 | TP53 (0.52) | PTPRCBCL2L1BADRXRARXRB | |
| SCHEMBL503529 | 0.84 | PTPRC (0.84) | PTPRCTSHRTTRSRD5A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104211689-B | Antiviral compounds | 吉利德制药有限责任公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-103977406-B | Antiviral compound | 吉利德制药有限责任公司 | 2016-10-19 | — | — | CN | disclosed |
| CN-104230900-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-24 | — | — | CN | disclosed |
| CN-104211689-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-17 | — | — | CN | disclosed |
| CN-104211713-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-12-17 | — | — | CN | disclosed |