Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.59 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.59 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | FRS2 | Q8WU20 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16342902 | 0.84 | FGFR1 (0.61) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL14861561 | 0.84 | FGFR1 (0.60) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL14863465 | 0.82 | FGFR1 (0.65) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL18055569 | 0.81 | FGFR1 (0.58) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL16342879 | 0.76 | FGFR1 (0.76) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL14862893 | 0.76 | FGFR1 (0.72) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL14863004 | 0.76 | FGFR1 (0.77) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL14861427 | 0.75 | FGFR1 (0.64) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL16342978 | 0.75 | FGFR1 (1.00) | FGFR1FLT1FGFR2FGFR4FGFR3 | |
| SCHEMBL16343060 | 0.75 | FGFR1 (0.80) | FGFR1FLT1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958500-A | Protein kinase inhibitors | ORION CORP | 2014-07-30 | — | — | CN | disclosed |