SCHEMBL27969760

SCHEMBL27969760

O=[SH](=O)Cc1cncnc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 1/20 0.34
HCAR2 Q8TDS4 1/20 0.33
PLA2G7 Q13093 2/20 0.32
GABRA1 P14867 1/20 0.32
GABRA5 P31644 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13909095 0.72 CYP1A2 (0.52)
SCHEMBL27838713 0.70 HCAR2 (0.39) HCAR2
SCHEMBL27792519 0.70 KDM4E (0.39)
SCHEMBL27765012 0.70 HTT (0.41) HCAR2
Hydrochloric Acid SCHEMBL27577369 0.70 CYP1A2 (0.50)
SCHEMBL25236225 0.70 CYP2A6 (0.38)
SCHEMBL27238079 0.70 POLB (0.40)
SCHEMBL28233280 0.70
SCHEMBL27911693 0.70 TYRO3 (0.31)
SCHEMBL456193 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203925-A 5-aminopyrimidine derivatives and use thereof for combating undesired plant growth BAYER IP GMBH 2014-12-10 CN disclosed
CN-102947289-B Arylethynyl derivatives HOFFMANN LA ROCHE 2014-06-11 CN disclosed