⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797109 | 1.00 | — | — | |
| SCHEMBL4446554 | 1.00 | — | — | |
| SCHEMBL559639 | 1.00 | — | — | |
| SCHEMBL4446556 | 1.00 | — | — | |
| SCHEMBL6182164 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL8123314 | 0.97 | — | — | |
| Bromide SCHEMBL11408199 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30218243 | 0.97 | — | — | |
| Phosphine SCHEMBL27570808 | 0.97 | — | — | |
| SCHEMBL28182951 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3417859-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | Abraxis BioScience, LLC (US) | 2018-12-26 | — | — | EP | claimed |
| EP-2481409-B1 | Nanoparticle comprising rapamycin and albumin as anticancer agent | ABRAXIS BIOSCIENCE LLC (US) | 2018-05-09 | — | — | EP | claimed |
| EP-2481402-B1 | Nanoparticle comprising rapamycin and albumin as anticancer agent | ABRAXIS BIOSCIENCE LLC (US) | 2018-05-09 | — | — | EP | claimed |
| EP-3810091-B1 | COMPOSITIONS FOR TREATING PULMONARY HYPERTENSION | ABRAXIS BIOSCIENCE LLC (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20250186359-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | ABRAXIS BIOSCIENCE, LLC | 2025-06-12 | — | — | US | disclosed |
| US-12324860-B2 | Methods of treating central nervous system disorders via administration of nanoparticles of an mTOR inhibitor and an albumin | ABRAXIS BIOSCIENCE, LLC (US) | 2025-06-10 | — | — | US | disclosed |
| US-20240299313-A1 | METHODS OF TREATING CENTRAL NERVOUS SYSTEM DISORDERS VIA ADMINISTRATION OF NANOPARTICLES OF AN MTOR INHIBITOR AND AN ALBUMIN | ABRAXIS BIOSCIENCE, LLC | 2024-09-12 | — | — | US | disclosed |
| US-11944708-B2 | Methods of treating central nervous system disorders via administration of nanoparticles of an mTOR inhibitor and an albumin | ABRAXIS BIOSCIENCE, LLC (US) | 2024-04-02 | — | — | US | disclosed |
| US-20240065984-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | ABRAXIS BIOSCIENCE, LLC (US) | 2024-02-29 | — | — | US | disclosed |
| US-20210322335-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | ABRAXIS BIOSCIENCE, LLC | 2021-10-21 | — | — | US | disclosed |
| US-20210315823-A1 | METHODS AND COMPOSITIONS FOR TREATING PULMONARY HYPERTENSION | ABRAXIS BIOSCIENCE, LLC | 2021-10-14 | — | — | US | disclosed |
| CN-102283826-A | Application of tretinoin and analogue thereof to treatment of tumour caused by inactivation of TSC1/TSC2 or activation of upstream pathway of TSC1/TSC2 | — | 2011-12-21 | — | — | CN | disclosed |
| CN-102085372-A | Application of Notch pathway inhibitor in treatment of tumors caused by activation of mTOR | INST BASIC MED SCIENCES PLA | 2011-06-08 | — | — | CN | disclosed |
| US-20100183728-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | ABRAXIS BIOSCIENCE, LLC | 2010-07-22 | — | — | US | disclosed |
| US-20100166869-A1 | METHODS AND COMPOSITIONS FOR TREATING PULMONARY HYPERTENSION | ABRAXIS BIOSCIENCE, LLC | 2010-07-01 | — | — | US | disclosed |
| CN-101730526-A | Nanoparticles comprising rapamycin and albumin as anticancer agents | ABRAXIS BIOSCIENCE LLC | 2010-06-09 | — | — | CN | disclosed |
| EP-2146707-A2 | METHODS AND COMPOSITIONS FOR TREATING PULMONARY HYPERTENSION | Abraxis BioScience, LLC (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-2131821-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | Abraxis BioScience, LLC. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008137148-A2 | METHODS AND COMPOSITIONS FOR TREATING PULMONARY HYPERTENSION | ABRAXIS BIOSCIENCE, LLC (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008109163-A1 | NANOPARTICLE COMPRISING RAPAMYCIN AND ALBUMIN AS ANTICANCER AGENT | ABRAXIS BIOSCIENCE, LLC. (US) | 2008-09-12 | — | — | WO | disclosed |