SCHEMBL27972754

SCHEMBL27972754

CO[Si](C)(C)CCCCCCCOCC1CO1

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.55
MAPK1 P28482 1/20 0.39
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31243541 1.00 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL5266157 0.98 TSHR (0.64) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL125938 0.93 TSHR (0.61) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23149854 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23149852 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706443 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706423 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706419 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706409 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706442 0.86 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104140826-B Aligning agent for liquid crystal, liquid crystal orientation film, phase retardation film and their manufacture method and liquid crystal display cells JSR株式会社 2018-01-23 CN disclosed
CN-104004528-B Aligning agent for liquid crystal, liquid crystal orientation film, liquid crystal display cells and its manufacture method JSR株式会社 2017-06-23 CN disclosed
CN-103980911-B Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal display cells and its manufacture method JSR株式会社 2017-03-01 CN disclosed
CN-105567259-A LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, LIQUID CRYSTAL DISPLAY DEVICE, POLYMER AND COMPOUND JSR CORP 2016-05-11 CN disclosed
CN-105086446-A Polymer composition, liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element, a manufacturing method of liquid crystal display element, and polymer JSR CORP 2015-11-25 CN disclosed
CN-102236209-B Producing method of liquid crystal display element, polymer composition and liquid crystal display element JSR CORP 2015-02-25 CN disclosed
CN-102241991-B Liquid crystal aligning agent, liquid crystal alignment layer manufacturing method and liquid crystal display device JSR CORP 2015-01-28 CN disclosed
CN-104232107-A Liquid crystal aligning agent, phase difference membrane and manufacturing method for phase difference membrane JSR CORP 2014-12-24 CN disclosed