Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.57 |
| ▸ | TXK | P42681 | 1/20 | 0.46 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.46 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27966434 | 0.84 | SYK (0.62) | SYKTXKKARS1SLK | |
| SCHEMBL373716 | 0.83 | KDM4E (0.61) | SYKTXKKARS1SLK | |
| SCHEMBL374050 | 0.82 | KDM4E (0.62) | SYKTXKKARS1SLK | |
| SCHEMBL374004 | 0.80 | SYK (0.58) | SYKTXKKARS1SLK | |
| SCHEMBL588953 | 0.79 | SYK (0.57) | SYKTXKKARS1SLK | |
| SCHEMBL589949 | 0.78 | SYK (0.53) | SYKTXKKARS1SLK | |
| SCHEMBL28812683 | 0.76 | SYK (0.50) | SYKTXKKARS1SLK | |
| SCHEMBL13407169 | 0.76 | SYK (0.51) | SYKTXKKARS1SLK | |
| SCHEMBL373789 | 0.73 | SYK (1.00) | SYKTXKKARS1SLK | |
| SCHEMBL3281453 | 0.72 | SYK (0.73) | SYKTXKKARS1SLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279110-B | heterocyclic compounds, medicaments containing said compounds, their use and processes for their preparation | 勃林格殷格翰国际有限公司 | 2019-12-10 | — | — | CN | disclosed |
| CN-104024244-A | Heterocyclic compounds, medicaments containing said compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM INT | 2014-09-03 | — | — | CN | disclosed |