Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.55 |
| ▸ | HTR1A | P08908 | 6/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615215 | 0.88 | MRGPRX4 (0.69) | MRGPRX4ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL12600498 | 0.87 | MRGPRX4 (0.60) | MRGPRX4ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL9739456 | 0.83 | KDM4E (0.64) | ABCB1ABCG2APPNPC1RAB9A | |
| SCHEMBL14878215 | 0.82 | MRGPRX4 (0.61) | MRGPRX4ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL28800848 | 0.82 | ABCB1 (0.55) | MRGPRX4ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL27889645 | 0.81 | ABCB1 (0.44) | MRGPRX4ABCB1HTR1ADRD2NPC1 | |
| SCHEMBL27889548 | 0.80 | MRGPRX4 (0.58) | MRGPRX4ABCB1HTR1ADRD2NPC1 | |
| SCHEMBL12600530 | 0.79 | MRGPRX4 (0.58) | MRGPRX4HTR1AAPPADRA1DADRA1A | |
| SCHEMBL5436452 | 0.79 | ABCB1 (0.49) | ABCB1HTR1ADRD2ABCG2 | |
| SCHEMBL27826128 | 0.78 | TDP1 (0.46) | ABCB1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102686555-B | Substituted 3-(phenoxymethyl) benzyl amines and personal care compositions | UNILEVER PLC | 2014-08-06 | — | — | CN | disclosed |