⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27649641 | 0.90 | — | — | |
| Benzene SCHEMBL27575942 | 0.73 | TP53 (0.35) | — | |
| Benzene SCHEMBL28246217 | 0.65 | — | — | |
| SCHEMBL27557510 | 0.65 | — | — | |
| SCHEMBL3861543 | 0.65 | — | — | |
| Benzene SCHEMBL28274055 | 0.60 | — | — | |
| Benzene SCHEMBL28019562 | 0.58 | TP53 (0.33) | — | |
| Benzene SCHEMBL28169481 | 0.58 | — | — | |
| Benzene SCHEMBL9562042 | 0.58 | — | — | |
| Benzene SCHEMBL4359019 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-B | Substituted 2-aminopyridine albuminoid kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP Co.,Ltd. (CN) | 2018-06-01 | — | — | CN | disclosed |
| CN-103965161-A | Substituted 2-aminopyridine inhibitor for protein kinase | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2014-08-06 | — | — | CN | disclosed |
| CN-103965168-A | Aryl/heteroaryl-substituted 2-aminopyridine inhibitor for protein kinase | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2014-08-06 | — | — | CN | disclosed |