⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221363 | 0.84 | — | — | |
| Furan SCHEMBL25381169 | 0.82 | MAPK1 (0.38) | — | |
| SCHEMBL1985537 | 0.80 | — | — | |
| SCHEMBL19432176 | 0.70 | — | — | |
| SCHEMBL7091762 | 0.67 | — | — | |
| SCHEMBL7091760 | 0.67 | — | — | |
| SCHEMBL179255 | 0.67 | — | — | |
| SCHEMBL9905529 | 0.64 | — | — | |
| SCHEMBL1423736 | 0.64 | — | — | |
| SCHEMBL4563756 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110418790-A | Imidazo pyrroles's ketone compound as p53-MDM2 inhibitor | LUOXIN BIOTECHNOLOGY SHANGHAI CO LTD | 2019-11-05 | — | — | CN | claimed |
| CN-105517996-B | Therapeutical active compound and its application method | 安吉奥斯医药品有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-107001236-A | The purification process and 1,5 pentanediamines of a kind of 1,5 pentanediamine | 上海凯赛生物技术研发中心有限公司 | 2017-08-01 | — | — | CN | claimed |
| EP-3157919-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2017-04-26 | — | — | EP | claimed |
| CN-105518001-A | MODIFIED BET-PROTEIN-INHIBITING DIHYDROQUINOXALINONES AND DIHYDROPYRIDOPYRAZINONES | Bayer Pharma AG | 2016-04-20 | — | — | CN | claimed |
| CN-105481857-A | Alpha-pinene derivative and preparation method and application thereof | UNIV GUANGDONG PHARM | 2016-04-13 | — | — | CN | claimed |
| WO-2015193219-A1 | BET-PROTEIN INHIBITING 3,4-DIHYDROPYRIDO[2,3-B]PYRAZINONES WITH META-SUBSTITUTED AROMATIC AMINO- OR ETHER GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-12-23 | — | — | WO | claimed |
| CN-105101970-A | Beta-lactamase inhibitors | VENATORX PHARMACEUTICALS INC | 2015-11-25 | — | — | CN | claimed |
| CN-102603615-A | Intermediates of 2-acetonyl-3-methoxy piperidine and preparation method of 2-acetonyl-3-methoxy piperidine | OCEAN UNIV CHINA | 2012-07-25 | — | — | CN | claimed |
| EP-2270006-A1 | Pyridazine derivatives useful as vanilloid receptor ligands | Amgen, Inc (US) | 2011-01-05 | — | — | EP | claimed |
| EP-0133612-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| EP-0221720-B1 | DIHYDROPYRIDINES | Pfizer Limited (GB) | 1990-06-27 | — | — | EP | claimed |
| EP-0118120-B1 | 1,4-DIHYDROPYRIDINE COMPOUND | NIKKEN CHEMICALS CO., LTD. (JP) | 1989-06-14 | — | — | EP | claimed |
| EP-0110073-B1 | PROCESS FOR THE PREPARATION OF TETRAHYDROPYRIDINES | BAYER AG (DE) | 1987-07-01 | — | — | EP | claimed |
| EP-0110259-B1 | 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0088274-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS PHARMACEUTICAL PREPARATIONS | BAYER AG (DE) | 1986-09-03 | — | — | EP | claimed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | claimed |
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | claimed |
| EP-0012180-B1 | 1,4-DIHYDROPYRIDINE COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS AND PREPARATION OF THESE COMPOSITIONS | BAYER AG (DE) | 1982-06-23 | — | — | EP | claimed |
| EP-0002208-B1 | NITRO 1,4-DIHYDROPYRIDINES, MEDICAMENTS CONTAINING THEM AND THEIR MANUFACTURE | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |