Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.49 |
| ▸ | HPGDS | O60760 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2709556 | 0.96 | PRCP (0.49) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL204800 | 0.96 | PRCP (0.49) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL28124521 | 0.92 | PRCP (0.50) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL19318875 | 0.92 | PRCP (0.46) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL27978605 | 0.90 | PRCP (0.50) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL16891281 | 0.89 | PRCP (0.51) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL27978462 | 0.88 | PRCP (0.50) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL28656576 | 0.87 | CYP3A4 (0.45) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL28656574 | 0.87 | CYP3A4 (0.45) | PRCPHPGDSCYP3A4CYP2C9NR1I2 | |
| SCHEMBL10215822 | 0.86 | PRCP (0.53) | PRCPHPGDSCYP3A4CYP2C9NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016971-B | Antiviral compound | PHARMASSET INC. (US) | 2016-05-25 | — | — | CN | disclosed |
| CN-103977406-A | Antiviral compounds | GILEAD SCIENCES INC | 2014-08-13 | — | — | CN | disclosed |