Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.70 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.70 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2673283 | 0.90 | PIK3CD (0.78) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL28813760 | 0.88 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2675830 | 0.87 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL27979105 | 0.87 | PIK3CD (0.72) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2673111 | 0.86 | PIK3CD (0.73) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL13050229 | 0.84 | PIK3CD (0.83) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2673598 | 0.84 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL10310060 | 0.83 | PIK3CD (0.81) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL2675263 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL27979223 | 0.82 | PIK3CD (0.74) | PIK3CDPIK3CBPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459272-B | Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use | GENENTECH INC | 2014-08-06 | — | — | CN | disclosed |