Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11153123 | 1.00 | CA1 (0.59) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL27979376 | 1.00 | CA1 (0.59) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL27854781 | 1.00 | CA1 (0.59) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL28630379 | 1.00 | CA1 (0.59) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL368624 | 0.98 | CA1 (0.61) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL28886675 | 0.98 | CA1 (0.61) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL29140926 | 0.94 | CA1 (0.50) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL28876748 | 0.93 | CA1 (0.52) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL1242297 | 0.93 | CA1 (0.52) | CA1CA9TSHRTP53ALDH1A1 | |
| Terephthalic Acid SCHEMBL1241165 | 0.93 | CA1 (0.52) | CA1CA9TSHRTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178658-A | Hydroxyethyl-terminated polyphenyl ether polyol modified polyurethane and preparation method thereof | 大连理工大学 | 2023-05-30 | — | — | CN | claimed |
| CN-107474490-A | Heparin tube environment-friendly type polyester master batch and preparation method thereof | 青岛金典生化器材有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-103965592-B | biodegradable polyester | TATUNG CO. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-103965592-A | Biodegradable polyester | TATUNG CO | 2014-08-06 | — | — | CN | claimed |
| CN-107474490-A | Heparin tube environment-friendly type polyester master batch and preparation method thereof | 青岛金典生化器材有限公司 | 2017-12-15 | — | — | CN | disclosed |
| CN-103965592-B | biodegradable polyester | TATUNG CO. (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103965592-A | Biodegradable polyester | TATUNG CO | 2014-08-06 | — | — | CN | disclosed |