Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1200372 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| SCHEMBL122295 | 0.82 | BLM (0.72) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| SCHEMBL202327 | 0.82 | BLM (0.72) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| SCHEMBL122296 | 0.82 | BLM (0.72) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL4331797 | 0.80 | BLM (0.70) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| Hydrochloric Acid SCHEMBL22462476 | 0.80 | BLM (0.70) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| Water SCHEMBL11329765 | 0.80 | BLM (0.70) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| Water SCHEMBL11327784 | 0.80 | BLM (0.70) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| SCHEMBL1272430 | 0.74 | SMN1; SMN2 (0.64) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 | |
| SCHEMBL6472726 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ABLMSLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039151-A | Cathepsin inhibitors for treating microglia-mediated neuron loss in the central nervous system | VIROBAY INC | 2014-09-10 | — | — | CN | disclosed |