Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15174343 | 1.00 | HCAR2 (0.50) | HCAR2KMT2AMEN1HRH3ALDH1A1 | |
| SCHEMBL15174342 | 0.93 | KMT2A (0.41) | HCAR2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL22847846 | 0.83 | HCAR2 (0.53) | HCAR2KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15174290 | 0.81 | HCAR2 (0.45) | HCAR2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL15174291 | 0.81 | HCAR2 (0.45) | HCAR2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL15173698 | 0.80 | HCAR2 (0.42) | HCAR2KMT2AMEN1HRH3ALDH1A1 | |
| SCHEMBL842816 | 0.80 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL15154700 | 0.80 | HCAR2 (0.42) | HCAR2KMT2AMEN1HRH3ALDH1A1 | |
| SCHEMBL2115608 | 0.78 | HCAR2 (0.47) | HCAR2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2115607 | 0.78 | HCAR2 (0.47) | HCAR2KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169261-A | Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use | XENOPORT INC | 2014-11-26 | — | — | CN | disclosed |