Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.57 |
| ▸ | JAK2 | O60674 | 4/20 | 0.50 |
| ▸ | AURKA | O14965 | 3/20 | 0.50 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | LYN | P07948 | 3/20 | 0.50 |
| ▸ | KIT | P10721 | 3/20 | 0.50 |
| ▸ | TEC | P42680 | 3/20 | 0.50 |
| ▸ | TXK | P42681 | 3/20 | 0.50 |
| ▸ | BMX | P51813 | 3/20 | 0.50 |
| ▸ | ITK | Q08881 | 3/20 | 0.50 |
| ▸ | TYK2 | P29597 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27982068 | 0.94 | BTK (0.59) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27857331 | 0.93 | BTK (0.59) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27982594 | 0.92 | BTK (0.67) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27982215 | 0.90 | BTK (0.53) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27982106 | 0.89 | BTK (0.56) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27982148 | 0.89 | BTK (0.59) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27857322 | 0.87 | BTK (0.60) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27982590 | 0.85 | BTK (0.64) | BTKJAK2AURKALCKLYN | |
| SCHEMBL123651 | 0.84 | BTK (0.70) | BTKJAK2AURKALCKLYN | |
| SCHEMBL27857248 | 0.84 | BTK (0.62) | BTKJAK2AURKALCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102325753-B | Carbazole carboxamide compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2014-09-10 | — | — | CN | claimed |