SCHEMBL27982200

SCHEMBL27982200

CN1CCN(C(=O)c2ccc3[nH]c4c(C(N)=O)ccc(-c5ccc6cc[nH]c6c5)c4c3c2)CC1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BTK Q06187 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27982572 0.85 BTK (0.74) BTK
SCHEMBL122285 0.85 BTK (1.00) BTK
SCHEMBL27982128 0.83 BTK (1.00) BTK
SCHEMBL27982116 0.82 BTK (0.79) BTK
SCHEMBL27982567 0.81 BTK (0.79) BTK
SCHEMBL27982618 0.81 BTK (0.72) BTK
SCHEMBL27982113 0.81 BTK (1.00) BTK
SCHEMBL147866 0.81 BTK (0.76) BTK
SCHEMBL27982053 0.80 BTK (1.00) BTK
SCHEMBL28795551 0.80 BTK (0.69) BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102325753-B Carbazole carboxamide compounds useful as kinase inhibitors BRISTOL MYERS SQUIBB CO 2014-09-10 CN claimed