⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27564331 | 0.98 | — | — | |
| SCHEMBL9644704 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL27721565 | 0.90 | — | — | |
| SCHEMBL27935931 | 0.86 | — | — | |
| SCHEMBL28185825 | 0.78 | — | — | |
| SCHEMBL28179376 | 0.78 | — | — | |
| SCHEMBL27571625 | 0.76 | — | — | |
| SCHEMBL28172563 | 0.75 | — | — | |
| SCHEMBL27469174 | 0.74 | — | — | |
| SCHEMBL27674234 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3991752-A1 | CELL-BINDING MOLECULE-TUBULYSIN DERIVATIVE CONJUGATE AND PREPARATION METHOD THEREFOR | Hangzhou Dac Biotech Co., Ltd (CN) | 2022-05-04 | — | — | EP | claimed |
| CN-114349843-A | Interleukin-2 derivative and preparation method and application thereof | 浙江博锐生物制药有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-108811499-A | Specific conjugation of cell binding molecules | 苏州美康加生物科技有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-107602882-A | A kind of halogen-free flame-retardant master batch and preparation method thereof | 成都硕屋科技有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-110312534-A | Antibody-drug-conjugates (ADC) with enzymatically cleavable groups | 拜耳制药股份公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110312533-A | Prodrugs of cytotoxic active agents having an enzymatically cleavable group | 拜耳公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-106117309-B | The inhibitor of Hepatitis C Virus | 吉利德制药有限责任公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-110072556-A | Specific Antibody Drug Conjugates (ADCs) with KSP Inhibitors | 拜耳制药股份公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110023316-A | Prepare the chemical method of imidazo pyrrolidinone derivatives and its intermediate | 诺华股份有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109562185-A | Novel conjugates of agents and moieties capable of binding to glucose-sensing proteins | 赛诺菲 | 2019-04-02 | — | — | CN | disclosed |
| CN-103826661-B | Novel binding agent-drug conjugates (ADCs) and uses thereof | 西雅图基因公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-108883195-A | Prodrugs of cytotoxic active substances with enzymatically cleavable groups | 拜耳制药股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107384441-A | Liquid-crystal composition and its manufacture method and the phase retardation film being made up of the liquid-crystal composition | 住友化学株式会社 | 2017-11-24 | — | — | CN | disclosed |
| CN-107236550-A | Liquid-crystal composition | 住友化学株式会社 | 2017-10-10 | — | — | CN | disclosed |
| CN-106957662-A | Liquid-crystal composition | 住友化学株式会社 | 2017-07-18 | — | — | CN | disclosed |
| CN-106536523-A | Expedient synthesis of sitagliptin | 斯特里奥肯公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-106458984-A | 5, 6-disubstituted pyridine-2-carboxamides as cannabinoid receptor agonists | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106163568-A | Antibody drug conjugates (ADC) containing spindle kinesin (KSP) | 拜耳制药股份公司 | 2016-11-23 | — | — | CN | disclosed |
| CN-103857658-B | Ethynyl derivatives serving as metabotropic glutamate receptor modulators | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104066330-A | Isoxazoline derivatives for controlling ectoparasites | LILLY CO ELI | 2014-09-24 | — | — | CN | disclosed |