Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937020 | 0.80 | MAPT (0.59) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL10962556 | 0.71 | HTT (0.65) | CYP2D6ALDH1A1HTTNPC1CA12 | |
| SCHEMBL3172394 | 0.69 | EPHX2 (0.54) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL5964054 | 0.69 | EPHX2 (0.54) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL6095040 | 0.69 | HTT (0.65) | CYP2D6ALDH1A1HTTNPC1CA12 | |
| SCHEMBL10963044 | 0.68 | HTT (0.69) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL5963579 | 0.68 | EPHX2 (0.56) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL3175750 | 0.68 | EPHX2 (0.56) | MAPTCYP2D6ALDH1A1EPHX2HTT | |
| SCHEMBL3208992 | 0.68 | NPC1 (0.64) | MAPTCYP2D6ALDH1A1HTTNPC1 | |
| SCHEMBL2861728 | 0.68 | MAPT (0.60) | MAPTCYP2D6ALDH1A1EPHX2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119273-A | Novel method for preparing dextromethorphan | SHANGHAI TIANCI BIOLOG VALLEY BIOLOG ENGINEERING CO LTD | 2014-10-29 | — | — | CN | disclosed |