⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979030 | 0.78 | — | — | |
| SCHEMBL17319732 | 0.68 | — | — | |
| SCHEMBL30804404 | 0.67 | — | — | |
| SCHEMBL27580360 | 0.67 | — | — | |
| SCHEMBL19171436 | 0.67 | — | — | |
| SCHEMBL515026 | 0.47 | — | — | |
| SCHEMBL5072565 | 0.40 | — | — | |
| SCHEMBL452580 | 0.40 | — | — | |
| Hydrogen Sulfide SCHEMBL28741033 | 0.38 | — | — | |
| Hydrogen Sulfide SCHEMBL29265424 | 0.38 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929337-A | A kind of preparation method of 4,5- thiazoline simultaneously [5,4-c] quinoline -2- amine | 上海应用技术大学 | 2018-12-04 | — | — | CN | claimed |
| CN-108779116-A | The inhibitor of Multiple Endocrine tumor albumen-MLL interactions | 生命医药公司 | 2018-11-09 | — | — | CN | claimed |
| CN-103709085-B | Pleuromulins microbiotic | SHANDONG HENRY MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-103709102-B | Containing whorled pleuromulins microbiotic | SHANDONG HENRY MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2015-08-12 | — | — | CN | claimed |
| CN-104513213-A | Fxr agonist | KBP BIOSCIENCES CO LTD | 2015-04-15 | — | — | CN | claimed |
| CN-102783482-B | 3-isothiazolinone composition | DALIAN BIO-CHEM CO., LTD. (CN) | 2014-10-22 | — | — | CN | claimed |
| CN-102783483-B | 3-isothiazolinone composition | DALIAN BIO CHEMICAL CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-103709085-A | Pleuromutilin antibiotics | KBP BIOSCIENCES CO LTD | 2014-04-09 | — | — | CN | claimed |
| CN-103709115-A | Pleuromutilin antibiotic derivatives | KBP BIOSCIENCES CO LTD | 2014-04-09 | — | — | CN | claimed |
| CN-103709093-A | Combined-ring-containing pleuromutilin antibiotics | KBP BIOSCIENCES CO LTD | 2014-04-09 | — | — | CN | claimed |
| US-20040152690-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2004-08-05 | — | — | US | claimed |
| US-20040082780-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2004-04-29 | — | — | US | claimed |
| WO-2004035549-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2004-04-29 | — | — | WO | claimed |
| US-20040038969-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2004-02-26 | — | — | US | claimed |
| WO-2004014871-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2004-02-19 | — | — | WO | claimed |
| WO-2004011417-A1 | N-BISARYL- AND N-ARYL-CYCLOALKYLIDENYL-ALPHA-HYDROXY-AND ALPHA-ALKOXY ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-02-05 | — | — | WO | claimed |
| WO-2003099284-A1 | AMINO-PYRIDINE, -PYRIDINE AND PYRIDAZINE DERIVATIVES FOR USE AS VANILLOID RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN | AMGEN INC. (US) | 2003-12-04 | — | — | WO | claimed |
| US-20030195201-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2003-10-16 | — | — | US | claimed |
| WO-2003049702-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2003-06-19 | — | — | WO | claimed |
| CN-1253554-A | Heterocyclic compounds and their use for inhibiting 'beta'-amyloid peptide | ELAN MEDICINE CO (US) | 2000-05-17 | — | — | CN | claimed |