Ethylene

Ethylene

SCHEMBL27986952

C=C.O=C(CCl)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.55
TSHR P16473 1/20 0.55
KMO O15229 3/20 0.54
POLB P06746 1/20 0.51
HPGD P15428 1/20 0.51
HTT P42858 1/20 0.51
HSD11B1 P28845 1/20 0.50
HDAC3 O15379 2/20 0.49
HDAC4 P56524 2/20 0.49
HDAC1 Q13547 2/20 0.49
HDAC7 Q8WUI4 2/20 0.49
HDAC2 Q92769 2/20 0.49
HDAC10 Q969S8 2/20 0.49
HDAC11 Q96DB2 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
HDAC6 Q9UBN7 2/20 0.49
HDAC9 Q9UKV0 2/20 0.49
HDAC5 Q9UQL6 2/20 0.49
SRD5A2 P31213 1/20 0.48
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5005689 0.96 GSK3B (0.59) GSK3BTSHRKMOPOLBHPGD
SCHEMBL29836035 0.96 GSK3B (0.59) GSK3BTSHRKMOPOLBHPGD
SCHEMBL9015106 0.81 TSHR (0.61) TSHRKMOPOLBHPGDHTT
SCHEMBL21055987 0.80 GSK3B (0.55) GSK3BTSHRKMOKDM4EALDH1A1
SCHEMBL8768769 0.80 GSK3B (0.55) GSK3BTSHRKMOKDM4EALDH1A1
SCHEMBL11392489 0.80 TSHR (0.55) TSHRKMOPOLBHPGDHTT
SCHEMBL1362599 0.79 TSHR (0.59) TSHRKMOPOLBHPGDHTT
SCHEMBL11658672 0.78 GSK3B (0.53) GSK3BTSHRKMOKDM4EALDH1A1
SCHEMBL2097486 0.78 GSK3B (0.53) GSK3BTSHRPOLBKDM4EALDH1A1
SCHEMBL22641091 0.78 GSK3B (0.53) GSK3BPOLBHPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104230875-A One-step method for preparing alpha-halogenated acetophenone glycol ketal compound UNIV HUANGSHAN 2014-12-24 CN disclosed