Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 8/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814728 | 1.00 | TNK2 (0.38) | TNK2GRM5STK17BSTK17AHCRTR1 | |
| SCHEMBL27987039 | 1.00 | TNK2 (0.38) | TNK2GRM5STK17BSTK17AHCRTR1 | |
| SCHEMBL18440370 | 0.96 | TNK2 (0.39) | TNK2GRM5STK17BSTK17ABTK | |
| SCHEMBL16336972 | 0.85 | STK17B (0.50) | STK17BSTK17AALDH1A1 | |
| SCHEMBL16336181 | 0.85 | STK17B (0.50) | STK17BSTK17AALDH1A1 | |
| SCHEMBL15055509 | 0.85 | STK17B (0.50) | STK17BSTK17AALDH1A1 | |
| SCHEMBL2906602 | 0.83 | BTK (0.34) | GRM5HCRTR1HCRTR2BTKCSF1R | |
| SCHEMBL15056902 | 0.81 | STK17B (0.51) | STK17BSTK17AALDH1A1KMT2AMAPT | |
| SCHEMBL16336962 | 0.81 | STK17B (0.51) | STK17BSTK17AALDH1A1KMT2AMAPT | |
| SCHEMBL16337923 | 0.81 | STK17B (0.51) | STK17BSTK17AALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169272-A | Pyrimidine-2,4-diamine derivatives as kinase inhibitors | CELLZOME LTD | 2014-11-26 | — | — | CN | disclosed |