Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17743754 | 0.82 | GAA (0.65) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1476618 | 0.82 | DEGS1 (0.64) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL20569301 | 0.82 | CYP1A2 (0.66) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL27986797 | 0.77 | MEN1 (0.43) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL27987224 | 0.76 | MEN1 (0.47) | GAAMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15971858 | 0.76 | GAA (0.66) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL22557301 | 0.76 | CYP1A2 (0.70) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30753576 | 0.76 | CYP1A2 (0.70) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL27472640 | 0.76 | CYP1A2 (0.66) | CYP1A2GAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13784015 | 0.74 | CYP1A2 (0.71) | CYP1A2GAAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104163792-A | N-picolinamide compound, preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | claimed |
| CN-104163792-A | N-picolinamide compound, preparation method and application thereof | HUNAN RES INST CHEMICAL IND | 2014-11-26 | — | — | CN | disclosed |