⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27591377 | 0.95 | TSHR (0.73) | — | |
| Dodecane SCHEMBL27722487 | 0.95 | TSHR (0.73) | — | |
| Hexane SCHEMBL11235960 | 0.84 | TSHR (0.70) | — | |
| Hexane SCHEMBL19638866 | 0.84 | TSHR (0.70) | — | |
| Hexane SCHEMBL1856720 | 0.84 | TSHR (0.70) | — | |
| Hexane SCHEMBL120113 | 0.84 | — | — | |
| Hexane SCHEMBL11134445 | 0.84 | — | — | |
| Hexane SCHEMBL7176091 | 0.84 | TSHR (0.70) | — | |
| Hexane SCHEMBL1849323 | 0.84 | TSHR (0.70) | — | |
| Hexane SCHEMBL8019627 | 0.84 | TSHR (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106011143-B | Specifically bind aptamer and its application of perforin | 中国人民解放军第三军医大学第二附属医院 | 2018-08-14 | — | — | CN | claimed |
| CN-104152449-B | MiRNA capture probes and its modified electrode and capture probe complementary strand and its carbon nano-tube modified golden magnetic nanoparticle compound | 中国人民解放军第三军医大学第二附属医院 | 2017-10-24 | — | — | CN | claimed |
| CN-106011143-A | Aptamer in specific binding with perforin and application of aptamer | 中国人民解放军第三军医大学第二附属医院 | 2016-10-12 | — | — | CN | claimed |
| CN-104152449-A | MiRNA capture probe, modifying electrode thereof, capture probe complementary strand, capture probe complementary strand modified carbon nanotube-gold magnetic nanoparticle compound | 2ND AF HOSP PLA 3RD MILITARY MEDICAL UNIV | 2014-11-19 | — | — | CN | claimed |
| CN-106011143-B | Specifically bind aptamer and its application of perforin | 中国人民解放军第三军医大学第二附属医院 | 2018-08-14 | — | — | CN | disclosed |
| CN-104152449-B | MiRNA capture probes and its modified electrode and capture probe complementary strand and its carbon nano-tube modified golden magnetic nanoparticle compound | 中国人民解放军第三军医大学第二附属医院 | 2017-10-24 | — | — | CN | disclosed |
| CN-106011143-A | Aptamer in specific binding with perforin and application of aptamer | 中国人民解放军第三军医大学第二附属医院 | 2016-10-12 | — | — | CN | disclosed |
| CN-104483362-A | Capture probe and signal probe modified electrode as well as preparation method and application thereof | 2ND AF HOSP PLA 3RD MILITARY MEDICAL UNIV | 2015-04-01 | — | — | CN | disclosed |
| CN-104152449-A | MiRNA capture probe, modifying electrode thereof, capture probe complementary strand, capture probe complementary strand modified carbon nanotube-gold magnetic nanoparticle compound | 2ND AF HOSP PLA 3RD MILITARY MEDICAL UNIV | 2014-11-19 | — | — | CN | disclosed |