Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27991139 | 0.93 | BRD4 (0.73) | BRD4HDAC6HDAC1 | |
| SCHEMBL27991025 | 0.90 | BRD4 (0.76) | BRD4HDAC6HDAC1 | |
| SCHEMBL27991000 | 0.85 | BRD4 (0.74) | BRD4 | |
| SCHEMBL15069664 | 0.85 | BRD4 (1.00) | BRD4 | |
| SCHEMBL27990743 | 0.81 | BRD4 (0.72) | BRD4HDAC6HDAC1 | |
| SCHEMBL28815231 | 0.78 | BRD4 (0.73) | BRD4 | |
| SCHEMBL15069145 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL25200280 | 0.77 | BRD4 (0.72) | BRD4 | |
| SCHEMBL27991011 | 0.77 | BRD4 (0.55) | BRD4 | |
| SCHEMBL19638491 | 0.77 | BRD4 (0.80) | BRD4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136435-A | BROMODOMAIN INHIBITORS | ABBVIE INC | 2014-11-05 | — | — | CN | claimed |
| CN-104136435-A | BROMODOMAIN INHIBITORS | ABBVIE INC | 2014-11-05 | — | — | CN | disclosed |