Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 20/20 | 0.83 |
| ▸ | AKT1 | P31749 | 11/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054683 | 0.91 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL15054173 | 0.91 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL15054800 | 0.91 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL15054840 | 0.91 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL15055065 | 0.90 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL16169601 | 0.88 | RPS6KB1 (0.82) | RPS6KB1AKT1 | |
| SCHEMBL16169599 | 0.88 | RPS6KB1 (0.82) | RPS6KB1AKT1 | |
| SCHEMBL27992577 | 0.86 | RPS6KB1 (0.77) | RPS6KB1AKT1 | |
| SCHEMBL15054739 | 0.85 | RPS6KB1 (1.00) | RPS6KB1AKT1 | |
| SCHEMBL15054627 | 0.85 | RPS6KB1 (1.00) | RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169258-A | Novel heterocyclic carboxamides as modulators of kinase activity | MERCK PATENT GMBH | 2014-11-26 | — | — | CN | disclosed |