Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800437 | 0.84 | TACR1 (0.54) | TACR1 | |
| SCHEMBL13200848 | 0.84 | TACR1 (0.54) | TACR1 | |
| SCHEMBL2800852 | 0.84 | TACR1 (0.54) | TACR1 | |
| SCHEMBL13201191 | 0.84 | TACR1 (0.54) | TACR1 | |
| SCHEMBL5747657 | 0.83 | TACR1 (0.38) | TRPV1TACR1 | |
| SCHEMBL17233113 | 0.76 | TACR1 (0.39) | TRPV1TACR1 | |
| SCHEMBL2797414 | 0.75 | TACR1 (0.68) | TACR1 | |
| SCHEMBL13200544 | 0.75 | TACR1 (0.68) | TACR1 | |
| SCHEMBL2799705 | 0.74 | TACR1 (0.40) | TRPV1TACR1 | |
| SCHEMBL5747877 | 0.72 | TACR1 (0.47) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | BAO JIANMING | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197724-A1 | 6.5 -PYRROLOPIPERIDINE TACHYKININ RECEPTOR ANTAGONISTS | TACR1, TACR2, HTR1D | TRPV1 219/4885TACR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.