Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997262 | 1.00 | PTPN11 (0.59) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL809252 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL433649 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL29384474 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL11546281 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL9869466 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL9869694 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL29504864 | 0.96 | HPGD (0.61) | PTPN11LMNAHPGDCYP1A2PGR | |
| SCHEMBL4331186 | 0.94 | NR5A1 (0.60) | PTPN11MAOBNR5A1NPC1RAB9A | |
| SCHEMBL5664514 | 0.94 | NR5A1 (0.60) | PTPN11MAOBNR5A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101080380-B | Process for the preparation of aliphatic chloroformates | SABIC INNOVATIVE PLASTICS IP | 2015-02-11 | — | — | CN | disclosed |