Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.68 |
| ▸ | USP28 | Q96RU2 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | PLG | P00747 | 4/20 | 0.35 |
| ▸ | KLK1 | P06870 | 4/20 | 0.35 |
| ▸ | KLK6 | Q92876 | 4/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997480 | 1.00 | NR3C2 (0.68) | NR3C2USP28RORCPLGKLK1 | |
| SCHEMBL2359055 | 0.90 | NR3C2 (0.70) | NR3C2AVPR2GPR27 | |
| SCHEMBL27997692 | 0.90 | NR3C2 (0.81) | NR3C2AVPR2GPR27 | |
| SCHEMBL2359163 | 0.90 | NR3C2 (0.81) | NR3C2AVPR2GPR27 | |
| SCHEMBL2358978 | 0.89 | NR3C2 (0.74) | NR3C2RORCAVPR2GPR27 | |
| SCHEMBL2357844 | 0.84 | NR3C2 (0.83) | NR3C2AVPR2GPR27 | |
| SCHEMBL2359033 | 0.84 | NR3C2 (0.83) | NR3C2AVPR2GPR27 | |
| SCHEMBL27997478 | 0.84 | NR3C2 (0.83) | NR3C2AVPR2GPR27 | |
| SCHEMBL2359096 | 0.83 | NR3C2 (0.69) | NR3C2RORCAVPR2GPR27 | |
| SCHEMBL2357001 | 0.81 | NR3C2 (1.00) | NR3C2AVPR2GPR27 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177137-B | 1-phenylpyrrole compounds | EXELIXIS INC | 2015-03-18 | — | — | CN | disclosed |