Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359248 | 1.00 | NR3C2 (0.81) | NR3C2ALDH1A1TMPRSS4AVPR2GPR27 | |
| SCHEMBL2551383 | 0.93 | NR3C2 (0.74) | NR3C2TMPRSS4MAPTNPSR1L3MBTL1 | |
| SCHEMBL2357294 | 0.91 | NR3C2 (0.67) | NR3C2ALDH1A1MAPT | |
| SCHEMBL2356581 | 0.89 | NR3C2 (1.00) | NR3C2TMPRSS4AVPR2GPR27MAPT | |
| SCHEMBL2360115 | 0.88 | NR3C2 (0.63) | NR3C2ALDH1A1AVPR2GPR27RORC | |
| SCHEMBL2551428 | 0.88 | NR3C2 (0.74) | NR3C2ALDH1A1TMPRSS4MAPTTP53 | |
| SCHEMBL16457022 | 0.87 | NR3C2 (0.62) | NR3C2TMPRSS4GPR27MAPTTP53 | |
| SCHEMBL2550462 | 0.86 | NR3C2 (0.69) | NR3C2MAPTTP53SMN1; SMN2NPSR1 | |
| SCHEMBL2548279 | 0.85 | NR3C2 (0.67) | NR3C2 | |
| SCHEMBL2358996 | 0.84 | NR3C2 (0.62) | NR3C2ALDH1A1AVPR2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177137-B | 1-phenylpyrrole compounds | EXELIXIS INC | 2015-03-18 | — | — | CN | disclosed |