Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001454 | 0.82 | ERN1 (0.56) | ERN1CTSB | |
| SCHEMBL1394957 | 0.81 | TDP1 (0.69) | ERN1TDP1NCOA1NCOA3GPR35 | |
| SCHEMBL311131 | 0.81 | ERN1 (1.00) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL31145561 | 0.81 | ERN1 (1.00) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL29114884 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL29114874 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL30661191 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL11417400 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM | |
| Potassium SCHEMBL30661194 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM | |
| SCHEMBL11417397 | 0.80 | ERN1 (0.96) | ERN1GPR35ALDH1A1APAF1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387217-B | Utilize naphthol derivative to prepare the method for adjacent hydroxyl naphthaldehyde compounds | NORTHWEST NORMAL UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-104387217-A | Method for preparing o-hydroxynaphthalene formaldehyde compound from naphthol derivative | UNIV NORTHWEST NORMAL | 2015-03-04 | — | — | CN | disclosed |