Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29542640 | 0.94 | — | — | |
| SCHEMBL33930 | 0.94 | — | — | |
| Hydrogen Sulfide SCHEMBL27401661 | 0.91 | KDM4E (0.43) | KDM4ENPC1TP53L3MBTL1KMT2A | |
| Bromide SCHEMBL27654949 | 0.91 | KDM4E (0.43) | KDM4ENPC1TP53L3MBTL1KMT2A | |
| Fluoride SCHEMBL27905734 | 0.91 | POLB (0.44) | KDM4ENPC1TP53L3MBTL1KMT2A | |
| Water SCHEMBL16702558 | 0.91 | KDM4E (0.43) | KDM4ENPC1L3MBTL1KMT2ARAB9A | |
| Water SCHEMBL28219863 | 0.91 | KDM4E (0.43) | KDM4ENPC1L3MBTL1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL28428483 | 0.91 | KDM4E (0.43) | KDM4ENPC1TP53L3MBTL1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7851378 | 0.91 | KDM4E (0.43) | KDM4ENPC1L3MBTL1KMT2ARAB9A | |
| SCHEMBL28334475 | 0.90 | TP53 (0.43) | KDM4ENPC1TP53KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334546-B | Novel ring-substituted N-pyridyl amides as kinase inhibitors | 诺华股份有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-104334546-A | Novel ring-substituted N-pyridyl amides as kinase inhibitors | NOVARTIS AG | 2015-02-04 | — | — | CN | disclosed |