Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430692 | 0.79 | CYP2B6 (0.30) | — | |
| SCHEMBL5440043 | 0.77 | CYP2B6 (0.33) | SMN1; SMN2ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL1266718 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL5440185 | 0.74 | HPGD (0.35) | HPGDCA12CA1CA9 | |
| SCHEMBL23887411 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20565115 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL3103737 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL20416441 | 0.71 | SMN1; SMN2 (0.32) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL17713882 | 0.70 | SMN1; SMN2 (0.38) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 | |
| SCHEMBL12928715 | 0.68 | SMN1; SMN2 (0.48) | SMN1; SMN2USP2ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007505874-A | — | — | 2007-03-15 | — | — | JP | claimed |
| EP-1664029-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | claimed |
| WO-2005026152-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | claimed |
| US-7764339-B2 | Liquid crystal display device | DAI NIPPON PRINTING CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| US-20090109376-A1 | Liquid Crystal Display Device | DAI NIPPON PRINTING CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |