Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003705 | 0.88 | NOX1 (0.45) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL20424966 | 0.81 | SNCA (0.46) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL29384027 | 0.80 | NOX1 (0.59) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL560873 | 0.80 | NOX1 (0.59) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL20444601 | 0.79 | NOX1 (0.54) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL15925823 | 0.79 | MAPT (0.46) | MAPTNOX1MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL28327041 | 0.78 | NOX1 (0.57) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL12003759 | 0.78 | NOX1 (0.57) | MAPTNOX1MEN1KMT2AGAA | |
| Water SCHEMBL3136465 | 0.78 | NOX1 (0.57) | MAPTNOX1MEN1KMT2AGAA | |
| SCHEMBL225916 | 0.77 | MAPT (0.59) | MAPTNOX1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529938-B | A kind of method synthesizing phenothiazine compound | 中山大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-104529938-A | Novel method for synthesizing phenothiazine compounds | UNIV SUN YAT SEN | 2015-04-22 | — | — | CN | disclosed |