Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674175 | 0.84 | — | — | |
| SCHEMBL1808824 | 0.68 | — | — | |
| SCHEMBL1386669 | 0.66 | — | — | |
| Acetic Acid SCHEMBL20875830 | 0.65 | FFAR3 (0.39) | ALDH1A1 | |
| SCHEMBL128452 | 0.64 | — | — | |
| SCHEMBL12294975 | 0.63 | GSK3B (0.47) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 | |
| SCHEMBL13737452 | 0.63 | KDM4E (0.36) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 | |
| SCHEMBL26672257 | 0.63 | — | — | |
| SCHEMBL25439036 | 0.62 | SMN1; SMN2 (0.36) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 | |
| SCHEMBL15881048 | 0.62 | CCNE1 (0.35) | MAPK10SMN1; SMN2CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603118-B | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators of the orphan nuclear receptor ROR γ | 菲尼克斯药品股份公司 | 2017-10-03 | — | — | CN | disclosed |
| CN-107007597-A | It is used as the thiazole of orphan nuclear receptor ROR γ instrumentalities through formamide or sulfonamide substitutions and the pharmaceutical applications of related derivatives | 菲尼克斯药品股份公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-104603118-A | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators of the orphan nuclear receptor ROR γ | PHENEX PHARMACEUTICALS AG | 2015-05-06 | — | — | CN | disclosed |