SCHEMBL2800533

SCHEMBL2800533

Oc1ccc(-n2nc3ccc(Cl)cc3n2)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
ESR1 P03372 3/20 0.40
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
GAA P10253 1/20 0.38
MCL1 Q07820 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 2/20 0.37
HTT P42858 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ESR2 Q92731 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GFER P55789 1/20 0.35
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383298 1.00 MAPT (0.41) MAPTNPC1RAB9AKDM4EATM
SCHEMBL17201891 0.88 NPC1 (0.42) MAPTNPC1RAB9AKDM4EESR1
SCHEMBL6930714 0.84 NPC1 (0.56) MAPTNPC1RAB9AKDM4EATM
SCHEMBL9638363 0.84 NPC1 (0.53) MAPTNPC1RAB9AKDM4EATM
SCHEMBL9638513 0.84 TRIM24 (0.42) MAPTNPC1RAB9AKDM4EMEN1
SCHEMBL29492118 0.84 TRIM24 (0.42) MAPTNPC1RAB9AKDM4EMEN1
SCHEMBL28556638 0.83 NPC1 (0.40) NPC1RAB9AESR1MEN1KMT2A
SCHEMBL29377081 0.82 POLB (0.50) MAPTNPC1RAB9AKDM4EATM
SCHEMBL3782539 0.82 POLB (0.50) MAPTNPC1RAB9AKDM4EATM
SCHEMBL11418479 0.81 NPC1 (0.51) MAPTNPC1RAB9AKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0478284-B1 Organic silicon compounds and cosmetic compositions SHINETSU CHEMICAL CO (JP) 1995-12-06 EP claimed
JP-11279523-A None JP disclosed
EP-3161528-B1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE ESSILOR INT (FR) 2020-03-04 EP disclosed
US-10370520-B2 Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive ESSILOR INTERNATIONAL (FR) 2019-08-06 US disclosed
CN-106459555-B Composition for manufacturing an ophthalmic lens comprising a UV absorber and an anti-yellowing additive 依视路国际公司 2019-03-22 CN disclosed
US-20170121498-A1 Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive ESSILOR INTERNATIONAL (FR) 2017-05-04 US disclosed
EP-3161528-A1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE Essilor International (Compagnie Générale D'Optique) (FR) 2017-05-03 EP disclosed
US-20170066969-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-03-09 US disclosed
EP-2960687-B1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE ESSILOR INT (FR) 2016-09-21 EP disclosed
EP-2960687-A1 Composition for the manufacture of an ophtalmic lens comprising an uv-absorber and an anti-yellowing additive ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2015-12-30 EP disclosed
US-4960898-A CONTAINING BENZOTRIAZOLE END GROUPS; ULTRAVIOLET ABSORBERS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-10-02 US disclosed
US-4690686-A HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US disclosed
EP-0208211-A2 Water-insoluble disperse dye composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-14 EP disclosed
US-4626257-A Method for dyeing polyester fiber materials: disperse dye combinations with compensated color fading SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-02 US disclosed
US-4584256-A AGING RESISTANCE RHONE-POULENC SYSTEMES (FR) 1986-04-22 US disclosed
EP-0164223-A2 Method for dyeing polyester fiber materials SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP disclosed
US-4271307-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-06-02 US disclosed
US-4076687-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-02-28 US disclosed
US-4028331-A POLYURETHANE RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-07 US disclosed
US-4028331-A POLYURETHANE RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-07 US disclosed