SCHEMBL2800537

SCHEMBL2800537

CCCCCCCCOc1ccc(C(=O)c2ccc(O)cc2O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.59
HTT P42858 1/20 0.56
MAOB P27338 5/20 0.55
KDM4E B2RXH2 1/20 0.54
LTA4H P09960 1/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
POLB P06746 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
THRA P10827 1/20 0.50
THRB P10828 1/20 0.50
PTPN11 Q06124 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654423 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4654426 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4653192 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4654539 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4654292 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4655433 1.00 NR5A1 (0.59) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4653220 0.99 HTT (0.57) NR5A1HTTMAOBKDM4ELTA4H
SCHEMBL4331186 0.96 NR5A1 (0.60) NR5A1MAOBLTA4HNPC1RAB9A
SCHEMBL5664514 0.96 NR5A1 (0.60) NR5A1MAOBLTA4HNPC1RAB9A
SCHEMBL30634381 0.96 NR5A1 (0.60) NR5A1MAOBLTA4HNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100201939-A1 PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME HOYA CORPORATION (JP) 2010-08-12 US claimed
EP-2172792-A1 PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME Hoya Corporation (JP) 2010-04-07 EP claimed
EP-1505412-B1 Plastic lens and process for producing the lens HOYA CORP (JP) 2008-11-05 EP claimed
US-7261845-B2 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2007-08-28 US claimed
US-20070141355-A1 Plastic lens and process for preparing the lens HOYA CORPORATION 2007-06-21 US claimed
EP-1521102-B1 Plastic lens and process for preparing the lens HOYA CORP (JP) 2006-12-27 EP claimed
EP-1521102-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-04-06 EP claimed
US-20050068492-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-31 US claimed
US-20050046967-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-03 US claimed
EP-1505412-A1 Plastic lens and process for producing the lens HOYA CORPORATION (JP) 2005-02-09 EP claimed
EP-3161528-B1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE ESSILOR INT (FR) 2020-03-04 EP disclosed
US-10370520-B2 Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive ESSILOR INTERNATIONAL (FR) 2019-08-06 US disclosed
CN-106459555-B Composition for manufacturing an ophthalmic lens comprising a UV absorber and an anti-yellowing additive 依视路国际公司 2019-03-22 CN disclosed
US-20170121498-A1 Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive ESSILOR INTERNATIONAL (FR) 2017-05-04 US disclosed
EP-3161528-A1 COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE Essilor International (Compagnie Générale D'Optique) (FR) 2017-05-03 EP disclosed
EP-1521102-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-04-06 EP disclosed
US-20050068492-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-31 US disclosed
US-20050068492-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-31 US disclosed
US-20050046967-A1 Plastic lens and process for preparing the lens HOYA CORPORATION (JP) 2005-03-03 US disclosed
EP-1505412-A1 Plastic lens and process for producing the lens HOYA CORPORATION (JP) 2005-02-09 EP disclosed